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1

Fluoroquinolone antibacterials: SAR, mechanism of action, resistance, and clinical aspects

Thomas D. Gootz, Katherine E. Brighty

Journal:

Medicinal Research Reviews

Année:

1996

Langue:

english

Fichier:

PDF, 3.31 MB

english, 1996

2

Ash and slag properties for co-gasification of sewage sludge and coal: An experimentally validated modeling approach

Schwitalla, Daniel, Reinmöller, Markus, Forman, Clemens, Wolfersdorf, Christian, Gootz, Matthias, Bai, Jin, Guhl, Stefan, Neuroth, Markus, Meyer, Bernd

Journal:

Fuel Processing Technology

Année:

2018

Langue:

english

Fichier:

PDF, 790 KB

english, 2018

3

Competition of different scattering channels in electron impact vibrational excitation of thin solid films of sulfur hexafluoride

B. Göötz, E. Burean, P. Swiderek

Journal:

Surface Science

Année:

2005

Langue:

english

Fichier:

PDF, 445 KB

english, 2005

4

Coupling power generation with syngas-based chemical synthesis

Forman, Clemens, Gootz, Matthias, Wolfersdorf, Christian, Meyer, Bernd

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 676 KB

english, 2017

5

CO 2 -to-X and Coal-to-X Concepts in Pulverized Coal Combustion Power Plants

Wolfersdorf, Christian, Forman, Clemens, Keller, Florian, Gootz, Matthias, Meyer, Bernd

Journal:

Energy Procedia

Année:

2017

Langue:

english

Fichier:

PDF, 361 KB

english, 2017

6

Über Fluor-Derivate von Kohlehydraten

Burckhardt Helferich, Richard Gootz

Journal:

European Journal of Inorganic Chemistry

Année:

1929

Langue:

german

Fichier:

PDF, 216 KB

german, 1929

7

Über einige neue 1-Acyl-Derivate der Glucose. Synthese des α-Benzyl-glucosids

Burckhardt Helferich, Richard Gootz

Journal:

European Journal of Inorganic Chemistry

Année:

1929

Langue:

german

Fichier:

PDF, 350 KB

german, 1929

8

Synthese eines Tetrasaccharid-acetats

Burckhardt Helferich, Richard Gootz

Journal:

European Journal of Inorganic Chemistry

Année:

1931

Langue:

german

Fichier:

PDF, 335 KB

german, 1931

9

Synthese des Saligenin-β-d-galaktosids

Burckhardt Helferich, Richard Gootz

Journal:

European Journal of Inorganic Chemistry

Année:

1932

Langue:

german

Fichier:

PDF, 206 KB

german, 1932

10

Electron-energy-loss spectroscopy of solid phenylacetylene

P. Swiderek, B. Göötz, H. Winterling

Journal:

Chemical Physics Letters

Année:

1998

Langue:

english

Fichier:

PDF, 110 KB

english, 1998

11

High-resolution electron-energy-loss spectroscopy of molecular multilayer film growth and properties

B. Göötz, O. Kröhl, P. Swiderek

Journal:

Journal of Electron Spectroscopy and Related Phenomena

Année:

2001

Langue:

english

Fichier:

PDF, 217 KB

english, 2001

12

Beitrag zur spätinfantilen Hallervorden-Spatzschen Krankheit

F. Seitelberger, E. Gootz, H. Gross

Journal:

Acta Neuropathologica

Année:

1963

Langue:

german

Fichier:

PDF, 2.50 MB

german, 1963

13

Zur Substruktur der Myoklonuskörper bei progressiver Myoklonusepilepsie (Typ Unverricht)

R. Schnabel, M. Gootz

Journal:

Acta Neuropathologica

Année:

1971

Fichier:

PDF, 1.64 MB

1971

14

Methoden für neurohistologische Untersuchungen des peripheren und autonomen Nervensystems an bioptisch gewonnenem Material

M. Gootz, F. Herzog, G. Lassmann, C. Reichert

Journal:

Acta Neuropathologica

Année:

1974

Langue:

german

Fichier:

PDF, 269 KB

german, 1974

15

Atypical inclusion bodies with myoclonic epilepsy

D. K. Dastur, B. S. Singhal, M. Gootz, F. Seitelberger

Journal:

Acta Neuropathologica

Année:

1966

Langue:

english

Fichier:

PDF, 1.76 MB

english, 1966

16

Bacteriological activity of trovafloxacin, a new quinolone, against respiratory tract pathogens

J. -C. Pechère, T. D. Gootz

Journal:

European Journal of Clinical Microbiology & Infectious Diseases

Année:

1998

Langue:

english

Fichier:

PDF, 860 KB

english, 1998

17

Vibrational excitation by electron impact in thin solid films of cyclopropane

B. Göötz, H. Winterling, P. Swiderek

Journal:

Journal of Electron Spectroscopy and Related Phenomena

Année:

1999

Langue:

english

Fichier:

PDF, 311 KB

english, 1999

18

The low-lying singlet-triplet transitions of phenylacetylene and styrene: Analysis of the vibronic structure

Petra Swiderek, Britta Göötz

Journal:

Berichte der Bunsengesellschaft für physikalische Chemie

Année:

1998

Langue:

english

Fichier:

PDF, 974 KB

english, 1998

19

ChemInform Abstract: Fluoroquinolone Antibacterials: SAR, Mechanism of Action, Resistance, and Clinical Aspects

T. D. GOOTZ, K. E. BRIGHTY

Journal:

Année:

1996

Fichier:

PDF, 25 KB

1996

20

The forgotten Gram-negative bacilli: What genetic determinants are telling us about the spread of antibiotic resistance

Thomas D. Gootz

Journal:

Biochemical Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 268 KB

english, 2006

21

Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone

Krisztina M. Papp-Wallace, Christopher R. Bethel, Thomas D. Gootz, Wenchi Shang, Justin Stroh, William Lau, Dale McLeod, Loren Price, Anthony Marfat, Anne Distler, Sarah M. Drawz, Hansong Chen, Emily

Journal:

Biochemical Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2012

22

Enterococcal virulence determinants may be involved in resistance to clinical therapy

Andrea Marra, Fadia Dib-Hajj, Lucinda Lamb, Frank Kaczmarek, Wenchi Shang, Gretchen Beckius, Anthony J. Milici, Ivette Medina, Thomas D. Gootz

Journal:

Diagnostic Microbiology and Infectious Disease

Année:

2007

Langue:

english

Fichier:

PDF, 338 KB

english, 2007

23

In vitro activity of CP-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial

Thomas D. Gootz, Katherine E. Brighty, Marge R. Anderson, Brenda J. Schmieder, Suzanne L. Haskell, Joyce A. Sutcliffe, Michael J. Castaldi, Paul R. McGuirk

Journal:

Diagnostic Microbiology and Infectious Disease

Année:

1994

Langue:

english

Fichier:

PDF, 708 KB

english, 1994

24

Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation

James M. Harrington, Tom Gootz, Mark Flanagan, Majinder Lall, John O’Donnell, Jennifer Winton, John Mueller, Alvin L. Crumbliss

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 574 KB

english, 2012

25

O496 Multiresistant Klebsiella pneumoniae from NYC hospitals contain β-lactamase KPC-2 or KPC-3 and porin changes

T. Gootz, F. Dib-Hajj, M. Lescoe, R. Huard, P. Della Latta

Journal:

International Journal of Antimicrobial Agents

Année:

2007

Langue:

english

Fichier:

PDF, 72 KB

english, 2007

26

Acinetobacter baumannii: an emerging multidrug-resistant threat

Gootz, Thomas D, Marra, Andrea

Journal:

Expert Review of Anti-infective Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 396 KB

english, 2008

27

Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine

McGuirk, Paul R., Jefson, Martin R., Mann, Douglas D., Elliott, Nancy C., Chang, Polly, Cisek, Eugene P., Cornell, C. Peter, Gootz, Thomas D., Haskell, Susan L.

Journal:

Journal of Medicinal Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 1.22 MB

english, 1992

28

Activity of Trovafloxacin Against Topoisomerases and GyrA/Gr1A Mutants ofStaphylococcus aureus

Dr Thomas D. Gootz, Richard P. Zaniewski, Suzanne L. Haskell, Frank S. Kaczmarek…

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 148 KB

english, 1999

29

Global dissemination of β2-lactamases mediating resistance to cephalosporins and carbapenems

Gootz, Thomas D

Journal:

Expert Review of Anti-infective Therapy

Année:

2004

Langue:

english

Fichier:

PDF, 210 KB

english, 2004

30

Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with an extended half-life and excellent tissue distribution.

Girard, A E, Girard, D, English, A R, Gootz, T D, Cimochowski, C R, Faiella, J A, Haskell, S L, Retsema, J A

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1987

Langue:

english

Fichier:

PDF, 1.56 MB

english, 1987

31

Action of Quinolones against Staphylococcus aureus Topoisomerase IV: Basis for DNA Cleavage Enhancement †

Anderson, Virginia E., Zaniewski, Richard P., Kaczmarek, Frank S., Gootz, Thomas D., Osheroff, Neil

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 179 KB

english, 2000

32

Depth and Angular Profiles of Inelastic Low-Energy Electron Scattering in Condensed Molecular Samples

Göötz, Britta, Popović, Duška B., David, Donald E., Michl, Josef, Swiderek, Petra

Journal:

Journal of Physical Chemistry B

Année:

2006

Langue:

english

Fichier:

PDF, 114 KB

english, 2006

33

The chemistry and biological profile of trovafloxacin

Brighty, K. E., Gootz, T. D.

Journal:

Journal of Antimicrobial Chemotherapy

Année:

1997

Langue:

english

Fichier:

PDF, 188 KB

english, 1997

34

Resistance to Cefamandole: Derepression of β-Lactamases by Cefoxitin and Mutation in Enterobacter cloacae

Thomas D. Gootz, Christine C. Sanders and Richard V. Goering

Journal:

The Journal of Infectious Diseases

Année:

1982

Langue:

english

Fichier:

PDF, 1.46 MB

english, 1982

35

Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents.

Barrett, J F, Gootz, T D, McGuirk, P R, Farrell, C A, Sokolowski, S A

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1989

Langue:

english

Fichier:

PDF, 2.42 MB

english, 1989

36

In vitro activity of CP-65,207, a new penem antimicrobial agent, in comparison with those of other agents.

Gootz, T, Retsema, J, Girard, A, Hamanaka, E, Anderson, M, Sokolowski, S

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1989

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1989

37

Cloning and Functional Characterization of an NAD+-Dependent DNA Ligase from Staphylococcus aureus

Kaczmarek, F. S., Zaniewski, R. P., Gootz, T. D., Danley, D. E., Mansour, M. N., Griffor, M., Kamath, A. V., Cronan, M., Mueller, J., Sun, D., Martin, P. K., Benton, B., McDowell, L., Biek, D., Schmid

Journal:

Journal of Bacteriology

Année:

2001

Langue:

english

Fichier:

PDF, 777 KB

english, 2001

38

Genetic and Molecular Characterization of -Lactamase-Negative Ampicillin-Resistant Haemophilus influenzae with Unusually High Resistance to Ampicillin

Kaczmarek, F. S., Gootz, T. D., Dib-Hajj, F., Shang, W., Hallowell, S., Cronan, M.

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2004

Langue:

english

Fichier:

PDF, 136 KB

english, 2004

39

Genetic Organization of Transposase Regions Surrounding blaKPC Carbapenemase Genes on Plasmids from Klebsiella Strains Isolated in a New York City Hospital

Gootz, T. D., Lescoe, M. K., Dib-Hajj, F., Dougherty, B. A., He, W., Della-Latta, P., Huard, R. C.

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2009

Langue:

english

Fichier:

PDF, 487 KB

english, 2009

40

Placement of alkyl substituents on the C-7 piperazine ring of fluoroquinolones: dramatic differential effects on mammalian topoisomerase II and DNA gyrase.

Gootz, T D, McGuirk, P R, Moynihan, M S, Haskell, S L

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1994

Langue:

english

Fichier:

PDF, 624 KB

english, 1994

41

In vitro assays used to measure the activity of topoisomerases.

Barrett, J F, Sutcliffe, J A, Gootz, T D

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1990

Langue:

english

Fichier:

PDF, 1.85 MB

english, 1990

42

Drug features that contribute to the activity of quinolones against mammalian topoisomerase II and cultured cells: correlation between enhancement of enzyme-mediated DNA cleavage in vitro and cytotoxic potential.

Elsea, S H, McGuirk, P R, Gootz, T D, Moynihan, M, Osheroff, N

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1993

Langue:

english

Fichier:

PDF, 1.49 MB

english, 1993

43

Development of resistance to cephalosporins in clinical strains of Citrobacter spp.

Gootz, T D, Jackson, D B, Sherris, J C

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1984

Langue:

english

Fichier:

PDF, 960 KB

english, 1984

44

Inhibitory effects of quinolone antibacterial agents on eucaryotic topoisomerases and related test systems.

Gootz, T D, Barrett, J F, Sutcliffe, J A

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1990

Langue:

english

Fichier:

PDF, 1008 KB

english, 1990

45

Pharmacokinetic studies of CP-74,667, a new quinolone, in laboratory animals.

Girard, D, Gootz, T D, McGuirk, P R

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1992

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1992

46

Comparison of three DNA hybridization methods for detection of the aminoglycoside 2"-O-adenylyltransferase gene in clinical bacterial isolates.

Gootz, T D, Tenover, F C, Young, S A, Gordon, K P, Plorde, J J

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1985

Langue:

english

Fichier:

PDF, 1.40 MB

english, 1985

47

Characterization of beta-lactamase induction in Enterobacter cloacae.

Gootz, T D, Sanders, C C

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1983

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1983

48

Biochemical characteristics and physiological significance of major DNA topoisomerases.

Sutcliffe, J A, Gootz, T D, Barrett, J F

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1989

Langue:

english

Fichier:

PDF, 1.56 MB

english, 1989

49

The current state of antibacterial research

Gootz, Thomas D

Journal:

Expert Review of Anti-infective Therapy

Année:

2003

Langue:

english

Fichier:

PDF, 52 KB

english, 2003

50

Development of two DNA probes for differentiating the structural genes of subclasses I and II of the aminoglycoside-modifying enzyme 3'-aminoglycoside phosphotransferase.

Young, S A, Tenover, F C, Gootz, T D, Gordon, K P, Plorde, J J

Journal:

Antimicrobial Agents and Chemotherapy

Année:

1985

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1985